Dexter Williams ran for three touchdowns, including a 97-yarder, and No. 6 Notre Dame beat No. 24 Virginia Tech 45-23 on Saturday night.
The Irish (5-0) will be seeking their third victory against a ranked team this season and their second in as many weeks.
Jerod Evans threw for 267 yards and two touchdowns and ran for another in intermittent snow and 20 mph winds, Joey Slye kicked a 20-yard field goal with 4:16 left and Virginia Tech rallied from a 17-point deficit to beat Notre Dame 34-31 Saturday.
An injury-marred opening week of college football began with Arizona star linebacker Scooby Wright tearing cartilage in his left knee and ended with Virginia Tech quarterback Michael Brewer breaking his collarbone.